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Abstract #0814

Detection of Brown Fat Thermogenesis by Hyperpolarized Xenon Gas MR

Rosa Tamara Branca1, Le Zhang2, Christian White1, Ting He1

1Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; 2Material Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

In vivo temperature measurement of fatty tissues by proton MR is notoriously challenging. Here we demonstrate in vivo temperature measurement by HP Xenon MR. We also show the possibility to directly measure in real time thermogenesis by brown adipose tissue, a tissue which has recently become the focus of much research attention due to its implication in the development of human obesity and type 2 diabetes.

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Keywords

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