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Abstract #0779

Study of the Variability of Short Association Bundles Segmented Using an Automatic Method Applied to a HARDI Database.

Edison Pardo1, Pamela Guevara1, Delphine Duclap2, Josselin Houenou2, Alice Lebois2, Benoit Schmitt2, Denis Le Bihan2, Jean-Franois Mangin2, Cyril Poupon2

1University of Concepcin, Concepcin, Chile; 2I2BM, CEA-Neurospin, Gif-sur-Yvette, France, France

The construction of an atlas of the human brain connectome, in particular, the cartography of fiber bundles of superficial WM is a complex an unachieved task. In this work we applied an automatic WM segmentation method proposed in the literature for the analysis of variability analysis of a big amount of superficial WM bundles. The method was applied to 20 subjects of a HARDI high quality database, adding several processing steps in order to improve the results. Then we studied the variability of 40 SWM fiber bundles from each hemisphere, and we constructed a model of these bundles in MNI space.

Keywords

acceleration acquisition adding aligned almost analyses analytical analyzed applied approaches artifacts association atlas automatic ball best better blue bold brain bundle bundles calculating cartography channel classified clustering coil combined computed conclude connecting constructed construction corrected cortex count database dataset defined density described describing detailed deterministic dual eddy entire errors evaluate example excitation exist existence exists expert fiber fibers fields filtered forward function future half head healthy hemisphere hemispheres human implemented improve improvement included inclusion index individual jean knowledge labeling lead least linear lists manual mask matrix million missing model next noise normalized optimized outliers oversampled oversampling parallel partial particular pixel placement population post preliminary previous processed processing project proposed protocol reduce registration regrouped reported resolution segmentation segmented selection several shape short similarly slices sources space spacing special spikes statistics step steps still streamline studied subject subjects superficial susceptibility system table task thresholded trio twenty unachieved variability verify volume volumes warped warping