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Abstract #0740

Spatial Working Memory in Attention Deficit Hyperactivity Disorder

Steffen Bollmann1, 2, Carmen Ghisleni1, 3, Ruth L. O'Gorman1, 3, Simon S. Poil1, 3, Peter Klaver, 34, Lars Michels1, 5, Juliane Ball6, Dominique Eich-Hchli7, Ernst Martin1, 3, Daniel Brandeis6, 8

1Center for MR-Research, University Childrens Hospital, Zrich, Switzerland; 2Center for Integrative Human Physiology (ZIHP), University of Zrich, Zrich , Switzerland; 3Center for Integrative Human Physiology (ZIHP), University of Zrich, Zrich, Switzerland; 4Institute of Psychology, University of Zrich, Zrich, Switzerland; 5Institute of Neuroradiology, University of Zrich, Zrich, Switzerland; 6Department of Child & Adolescent Psychiatry, University of Zrich, Zrich, Switzerland; 7Psychiatric University Hospital, University of Zrich, Zrich, Switzerland; 8Central Institute of Mental Health Mannheim, Medical Faculty Mannheim/ Heidelberg University, Mannheim, Germany

Since working memory deficits play an important role in ADHD we developed a spatial working memory task to examine differences in brain activity between adults and children with ADHD and controls. In a fMRI study we investigated adults and children with and without ADHD to understand the underlying developmental deficits seen in ADHD. Our results suggest that the working memory networks are not yet fully developed in children and that ADHD subjects do not recruit a larger network to handle increased working memory demand, unlike control subjects.

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Keywords

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