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Abstract #0474

in vivo Active Visualization of an Ablation Guidewire for the Revascularization of Occlusive Arterial Disease

Kevan Anderson1, Nicolas Yak1, Labonny Biswas1, Jennifer Barry1, Graham Wright1, 2

1Physical Sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Studies investigating the use of MRI for lesion revascularization have focused on the development of specialized active catheters and guidewires that incorporate receive coils to enable device visualization. There are many engineering challenges associated with this approach and the added complexity will typically limit device performance. In this study we evaluate the ability to actively visualize a commercially available radio-frequency ablation guidewire in an animal model of occlusive arterial disease. The selected technique utilizes an external coupling device that is magnetically coupled to the guidewire and the capacity to visualize the guidewire in vivo is demonstrated.

Keywords

ability ablation active addition adequate advanced anatomical animal animals approximately around arterial artery assessed audience biophysics cable carotid catheters challenge characteristics clearances clinical coated coil coils compensate conductive copper core couples coupling created cross currently cylindrical degree depict depicted depicting developing development device devices diameter disease dual enable enables enabling encountered ends entry excitation existing floating formation frequency future give gradient guidance guided heating hollow hurdles identify improved in vivo inability incorporate infer inserted inside instruments investigating length lesion lesions limited localized location longitudinal loss magnetically making medical minimize model models modifications near neck need noted novel occluded occlusion occlusive orientation overall passed path percutaneous performance physical pigs placed position procedural projection proximal pursue received reconstructed reduction refocusing regulatory rendered represents researchers resonant respect sciences seated sectional slice soft specialized studies success surface suture swine target thereby tissue towards trap tying typically utilizes utilizing vascular vessel visible visualization visualize visualized wire wright yield