Meeting Banner
Abstract #0285

Temperature and Perfusion Monitoring During RF Heating of the Human Calf Muscle

Frank F.J. Simonis1, Esben Thade Petersen1, Alexander J.E. Raaijmakers1, Jan J.W. Lagendijk1, Cornelis A.T. van den Berg1

1Radiotherapy, UMC Utrecht, Utrecht, Netherlands

Recent simulation studies indicate that in clinical MRI experiments local tissue temperature and RF exposure can exceed safety guidelines. By using PRFS MR thermometry and ASL, one can monitor rises in tissue temperatures and perfusion. By combining these techniques during RF heating, we hope to obtain insight in the local thermoregulatory system of the body. Temperature measurements in the calf muscle during a high SAR scan at clinical settings showed that RF heating can lead to significant heating of the outer region of the calf muscle. An increase in perfusion was also detected, in spite of very low perfusion levels.

Keywords

absorption according accurate addition allowed amplitude applied approximately arises around assigned background better birdcage body border calf cause clear clearly clinical coil column comes compensated compensation complex concluded conditions contrast control core database delay destructive determination deviation dimensions directly done drift drive duke duty electric electromagnetic elements equation equilibrium even exceed excitation exercise experiment experimental exposure extremities family fatigue flow frank frequency generic global good guidelines heating help hope human importance induce induced input inside involved knee largest lier local magnet making male manually maps match materials measure measured minimal minutes model monitoring muscle neglected next noninvasive occurring opportunity optical outer patient perfusion placed power preceded predominantly probes pronounced properties proving pulse pulsed quantifies radiotherapy refs regulatory related resolution respectively rest rises safety scanned scanner sense settings simulated simulation simulations skin slice spatially starting subject sunflower surrounding system table temperature temperatures thermometry tissue topic understanding varying virtual volunteer volunteers water wrapped