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Abstract #0008

3D Hemodynamics in Intracranial Aneurysms: Influence of Size and Morphology

Susanne Schnell1, Sameer A. Ansari1, 2, Parmede Vakil1, 3, Marie Wasilewski1, Maria L. Carr1, Michael C. Hurley1, 2, Bernard R. Bendok2, Hunt Batjer2, Timothy J. Carroll1, 3, James C. Carr1, Michael Markl1, 3

1Radiology, Northwestern University, Chicago, IL, United States; 2Neurological Surgery, Northwestern University, Chicago, IL, United States; 3Biomedical Engineering, Northwestern University, Evanston, IL, United States

Characterization of 3D blood flow demonstrated the influence of lesion size, shape and type on aneurysm hemodynamics suggesting the potential of 4D-flow MRI to assist in the classification of individual aneurysms.

Keywords

abuse alcohol although aneurysm aneurysms annual arranged assessment assist associating biomedical blood brain central channels characteristics clinics coded color combination complex components comprehensive conditions consistent contour contrast correlation cubic date defined described description detect develop diagnostic differentiate dimension disease distinct distribution distributions diverse empirical evaluate flow fluid forces foundation fusiform future generally giant gradient grant graphs histogram hypertension improved in vivo included incomplete indicating individual influence inter intra king largest lesion life location longitudinal lowest major maria markers mechanics morbidity morphology mortality narrow neurological northwestern note noted occur outlook patient patients patterns peak peripherally planning population potential previously prominent providing quantification quantitative radiology ranging relationship representative resolution resolved revealed review risk rupture ruptured segmentation segmented shear significantly sites slow smaller smoking spatial spline status stratification stress stroke studies substantially subtle suggesting summarized surface surgery systematic systemic systems temporal therapy threatening timothy transecting typically utility vector velocities velocity vessel visualization vorticity wall white years