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Abstract #4428

Proton-Decoupled 13C MRS of the Breast at 7T

Sergey Cheshkov1, 2, Ivan Dimitrov3, 4, Joseph Rispoli5, Elias Gonzalez5, Craig Malloy1, 6, Mary McDougall, 57, Steve Wright, 57

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 2Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States; 3Philips Medical Systems, Cleaveland, OH, United States; 4Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States; 5Biomedical Engineering, Texas A&M University, College Station, TX, United States; 6Radiology, University of Texas Southwestern Medical Center, Dallas, TX, United States; 7Electrical Engineering, Texas A&M University, College Station, TX, United States

Studies indicate that composition of breast fat, which is sensitive to diet, may predispose to cancer with ω6/ω3 lipid ratio being of particular importance. We demonstrate for the first time artifact free proton-decoupled breast 13C MRS at 7T using home built 1H/13C breast coil. This approach has the potential to provide ω6/ω3 information on lipid composition, which may shed further light on the relations between obesity, diet, and cancer. Further improvements in 13C coil sensitivities may be required in order to achieve higher SNR and shorter acquisition times.

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Keywords

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