Mass Spectrometry Detection of Loss of Structural Integrity of Gd-DTPA Entrapped in J774 Machrophages

Keywords

ability accurate acquisition added adding additional agents aliquots amount analyzed apparently appear appears appropriate atmosphere attack available behavior carried cell cells cellular centrifuged characterization chemistry chosen commercially complex complexes concentration confinement continuum contrast conversely currently cycling days detection determined dismantled display endowed entrapped enzymatic exploit extensively fast fate fibroblasts fibrosis field filtered final form fragments frequencies frequently fresh glance herein hours importance in vivo incubated incubation insight insights intact integrated integrity intensities internal internalization internalized iron lanthanide largely leads ligand living long longer loss machinery macrophages maintain mass matrix media mode molecular molecules negative newton oxide pathologies pathway payload positive post profiles proton quadruplicate quantification ranging reflects registration related release report reported respect resuspended rigidity robust samples seems several short shortening similarity solution spectrometric spectrometry stabilities stability stable strengths structural systemic systems thermodynamic threshold topic tracking transform transformation transformed treated types understanding untreated upon upsurge uptake usually viability volume washed water waters whereas