In Vivo Biochemical Imaging of HCC Tumor Bearing Rats Using Hyperpolarized [1-13C]pyruvate and 18F-FDG

Keywords

according achieved active activity acute addition alanine amount analyzed anatomical anesthesia animal animals assessment attenuation bearing best biochemical blood brindle cell coil colleagues combination comparable consecutive contrast corrected correlation days decay decreases delivery described detected detection diameter display dissolved downstream dual dynamic easily energy evaluated excite explain gastrointestinal global glucose grade grant grown growth hand healthy hypoxia ideal in vivo individual induced injected injection integrated integration intensities intestines kidney kinetic label lack lactate liquid local location martin mayer metabolic metabolically metabolism metabolite metabolites metabolized minutes modeling much muscle necrosis necrotic normalized nuclear organs oxford part peak perfused peripheral physiological placed polarization position press pressure presumably processes proposed proton quality randoms rats reached received reconstructed reconstruction regarding relation reported scanner serving sets shot significantly simple slice smaller spectrum spiral stage statistically strength strong subcutaneous subgroup surrounding tail target tissue tract transferred tumor tumors tuned turnover uptake variability varying vein vessel visible visual vital whereas