Using Pyruvic Acid as a Solvent for Dynamic Nuclear Polarization Sample Preparation

Keywords

abundance account achieve achieved acid acids added addition adequate administration agents alone already although amino amorphous animals appropriate approximately ascending assess become biophysics buildup cancer careful cellular clinical coil concentration concentrations concept considerably constant degree deionized determined dissolution dissolve dissolved distribution doped doping dose dual dynamic either electronic enables enriched enzyme equilibrium evaluations experiment exploratory expression favorable feasibility feasible fold free gain glass glassing glycerol health human humans in vivo injected injection instruments investigate labeled like liquid matrix media mediated medical metabolism methionine mixture molecules natural neat neutralize nuclear opportunity organic others oxford patients phys polarization polarizations polarized polarizer potential preparation prepare prepared previous previously probing profile profiles prostate protocol prove pulse radical rapid reactions receiving recently representative require requirements safety sample samples scanner sciences shortened sigma slightly sole solid solids solution solvent solvents spectra spins studies subjects substrate substrates summarized temperature thermal tolerability trial tuned typically uniform utilized vessel water