Meeting Banner
Abstract #4285

Towards Interactive Super-Resolution Reconstruction of Whole-Body MRI Mouse Data

Artem Khmelinskii1, Esben Plenge2, Peter Kok3, 4, Dirk Poot2, Oleh Dzyubachyk3, Charl P. Botha4, Ernst Suidgeest5, Wiro Niessen2, 6, Louise van der

1Division of Image Processing, Dept. of Radiology, LUMC, Leiden, The Netherlands, Leiden, Zuid-Holland, Netherlands; 2BIGR, Depts. of Radiology and Medical Informatics, ErasmusMC, Rotterdam, Netherlands; 3Division of Image Processing, Dept. of Radiology, LUMC, Leiden, Netherlands; 4Data Visualization Group, Dept. of Mediamatics, TU Delft, Netherlands; 5Dept. of Radiology, Molecular Imaging Laboratories Leiden, Section Nuclear Medicine, LUMC, Leiden, Netherlands; 6Quantitative Imaging Group, Dept. of Imaging Science & Technology, TU Delft, Netherlands; 7Depts. of Anatomy & Embryology, LUMC, Leiden, Netherlands

We present a new approach for producing highly resolved, localized isotropic volumes-of-interest in whole-body mouse MRI. This enables interactive HR visualization and exploration of anatomical structures in MRI. The idea is similar to that of well-known web-based geographical maps, where it is possible from a global overview image to zoom in on a detail of interest. Such functionality is relevant in a biomedical setting when working with high-resolution volumetric data. Using the method presented in this paper, from a global LR image the user can interactively zoom in on a sub-volume of interest.

Keywords

agreement aliasing anatomical anatomically anatomy applied applying approximately approximation articulated atlas biomedical body bone bones chest clearly collected conjugate considerably consisted contains correspondent datasets degrees delft dept detail developing differ direct disadvantage distinct division employs enables encouraging entire fashion field fitted functionality generally geographical global going graphics grid hardware head heavy highly humerus idea illustrated improvement increasing instead interactive interactively inverse involves iterative joint joints labeled laboratories landmarks least local make manual mapped mice minutes model mouse noticeable novel nuclear overview pelvis peter post powerful problem processing producing proposed published quality quantitative radiology radius realistic recent reconstruct reconstructed reconstruction reduces reformation regularization relevant requires resolution resolved rotated sample samples sampling scale scanned scanner section segmentation segmented segments select setting since slice slices smoothness solution space specified spectral squares stack standardized stitching structures subsequent substantial super system technology term tibia together towards transformation typical uniform user visualization volume volumes volumetric whole zoom