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Abstract #4275

Accelerated Variable Flip Angle T1 Mapping Via View Sharing of Pseudo-Random Sampled Higher Order K-Space

Jason Su1, Manojkumar Saranathan1, Brian Rutt1

1Department of Radiology, Stanford University, Stanford, CA, United States

A view-sharing methodology in which higher order k-space samples are shared between data frames is applied along the flip angle dimension of a variable flip angle T1 mapping sequence to achieve an acceleration of 2.3x with nearly negligible loss in T1 estimation. The composite-derived maps had a percent error median of 0.104% and a 5-to-95 percentile range of -5.216% to 5.192%. Composite image quality and T1 map fidelity was dramatically improved by correcting mixed data with a scale factor based on values in the fully sampled center of k-space. The 5-to-95 percent error range shrank by a factor of 1.67.

Keywords

accelerate accelerated acceleration accomplished according accuracy achieved acquisition adding addition adjacent allow angiography applied artifacts attention borrowed brain careful caused changing channel chosen closest coil collected collection compatible composite composites compressed computing consuming contrast correction covered create curves decrease derived designed despot directly dramatically easily encode equation error especially essentially existing extracted extraction facsimile fidelity fitting fold frames fully gains gradient greater head healthy improved incoherent indistinguishable interleaved jumps lengthier like linear linearizing loss magnitudes manner many mapping maps matrix median medical milliseconds missing mixed mixing modest need neighboring neighbors occur omitted originals outer overall overlap parallel patterns percent peripheral precision produced pseudo quantitative quick radiology random randomly rapidly reconstruct reconstructed reconstruction reductions registration reliably remains respectively responsible sampled samples sampling scale scaling scanner scheme seems series shared sharing sharp simple simply slice sought space speed spoiled succession support synthesize target third tissue transition true underestimation uniformly variable variations view volunteer