Meeting Banner
Abstract #4157

High-Quality Clinical MRI Massively Accelerated with Segmented Echo-Planar Readout and Phase-Cycled Reconstruction

Nan-kuei Chen1

1Brain Imaging and Analysis Center, Duke University, Durham, NC, United States

Every year millions of patients (e.g., children, seriously ill patients and claustrophobic individuals) cannot complete lengthy MRI procedures without sedation or anesthesia, which poses significant risks for serious adverse effects and harm to health. It is highly desirable to design a novel approach to enable millions of patients to complete clinical MRI without the risk of adverse effects associated with sedation / anesthesia. Here we demonstrate that many clinical MRI sequences may be massively accelerated with segmented echo-planar readout, and high-quality data can be reliably obtained by removing the echo-planar related phase errors with a novel phase-cycled reconstruction algorithm.

Keywords

accelerate accelerated acceleration achieved acquiring acquisition address adverse among anesthesia anesthetic arrest arteries artifact artifacts assess brain cardiac challenging children claustrophobic clinical complete contrast contrasts correction cycled decay degree delirium dependence design desirable developed dimensional distortions distress dual duke effectively efficiency eliminate emotions enable errors every example excitation experimental feasible flair fold function geometric harm health healthy highly ignorable individuals inherent injury insignificantly integrated issue length lengths lengthy linearly long major many massively matrix millions mood needing nerves north noticeable novel numerical optimal others oxygen parallel particularly patient patients period periods planar populations poses post procedures processing produced proportional protocol protocols prove providing pulse quality readout reconstruction reduce reduced related reliably remove removed removing requiring respiratory risk risks sacrificing scanners scheme sedation segmented series serious seriously short shorten significantly slice song spin spread strongly studies suggest susceptibility susceptible throughput train trains usually valuable various veins virtually volunteers warp waveform waveforms year