Meeting Banner
Abstract #4130

Clinical Significance of Lipid Peak in In-Vivo 1H-MR Spectroscopy of Uterine Sarcomas at 3T

Mayumi Takeuchi1, Kenji Matsuzaki1, Masafumi Harada1

1Department of Radiology, University of Tokushima, Tokushima, Japan

We evaluated 14 uterine sarcomas and 24 benign myometrial lesions by 1H-MR spectroscopy at 3T. High lipid peaks were observed in 12 of 14 sarcomas, whereas in none of benign lesions except for one lipoleiomyoma. The choline peaks were observed in 12 of 14 sarcomas, whereas in all 24 benign lesions. However massive necrosis in sarcomas may decrease the choline peak, the presence of high lipid peak may suggest their malignant nature. We conclude that high lipid peak in uterine mass without fatty component is suggestive for sarcoma, whether the choline peak is present or not.

Keywords

activity almost array atypical benign bimodal body cancer cancers cause cells cellular cervical choline classes classified clinical coagulated coils component components concentration conclude contain contained contribute corpus cystic decrease diagnosed differentiation difficult distinguish electric evaluated examination fatty general grade gynecologic heterogeneous histological hyperplasia hypothesized in vivo intensity japan lesion lesions lipid malignancy malignant mass massive materials metabolic metabolite much nature necrosis necrotic noise none often pathologically peak peaks placed polyps presence press radiology referring reflecting retrospectively revealed sarcoma sarcomas significance significantly solid spectroscopy subjects suggest suggestive superconducting system tend tissue torso tumor tumors twofold typical undifferentiated units useful uterine viable visualized visually whereas whether