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Abstract #4105

Histologically-Validated Bladder Cancer Staging with Magnetic Resonance Imaging at 3T

Huyen Thanh Nguyen1, 2, Guang Jia1, Zarine K. Shah1, Kamal S. Pohar3, Amir Mortazavi4, Debra Zynger5, Michael V. Knopp1

1Wright Center of Innovation in Biomedical Imaging, Department of Radiology, The Ohio State University, Columbus, OH, United States; 2Biophysics Program, The Ohio State University, Columbus, OH, United States; 3Department of Urology, The Ohio State University, Columbus, OH, United States; 4Department of Internal Medicine, The Ohio State University, Columbus, OH, United States; 5Department of Pathology, The Ohio State University, Columbus, OH, United States

Purpose: to investigate the capability of 3T MRI in accurately staging bladder cancer. Methods: all scans were performed with T2w before DCE MRI. With defined staging criteria, a radiologist staged bladder tumors by using T2w images, and then DCE data. Results: staging of T2/lower by using T2w images and DCE data had high sensitivities (80% and 90%), specificities (82% and 73%), and accuracies (81% and 81%). The overall accuracy of staging with T2w and DCE MRI were 71% and 81%, respectively. Conclusion: 3T MRI with the potential to accurately stage bladder cancer can make a major impact on the patient outcome of cystectomy.

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Keywords

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