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Abstract #4019

Accuracy of Gadoxetic Acid-Enhanced Magnetic Resonance Imaging for the Diagnosis of Sinusoidal Obstruction Syndrome in Patients with Chemotherapy-Treated Colorectal Liver Metastases

Na-Young Shin1, Myeong-Jin Kim1, Joon Seok Lim1, Mi-Suk Park1, Yong-Eun Chung1, Jin-Young Choi1, Ki Whang Kim1, Young-Nyun Park1

1Yonsei University Severance Hospital, Seoul, Korea, Republic of

To assess whether hepatobiliary phase images of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) is a diagnostic finding of sinusoidal obstruction syndrome (SOS) in patients with hepatic metastases who have undergone chemotherapy, we retrospectively analysed EOB-MRI of 42 patients who had undergone chemotherapy before hepatic resection of colorectal hepatic metastases using a 5-point scale. Reticular hypointensity on hepatobiliary phase images of EOB-MRI is highly specific for the diagnosis of SOS in patients with treated colorectal hepatic metastases with good interobserver agreement.

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Keywords

abbreviations accuracy acid arrows assess asterisks characteristic characteristics chemotherapy confidence congestion curve definite degrees determine diagnosis diagnostic enhanced examination false fibrosis finding fine hepatic highly histological histology homogeneous hospital intensity intervals kappa lesions limited liver localized marked metastases metastatic minimal negative nodular objective observer obstruction obstructive occurred operating parentheses park patient patients positive predictive presence prominent radiologists reader readers received receiver republic resection reticular reticulation reticulations retrospectively reviewed reviewer scale sections sensitivity severance shin sinusoidal specificity subtle syndrome table treated unaware undergone various whether young