Meeting Banner
Abstract #3941

Evaluation of the Relationship Between Right Ventricle Mechanics and Pulmonary Artery Vessel and Flow Dynamics in Pulmonary Artery Hypertension by MRI

El-Sayed H. Ibrahim1, Abubakr A. Bajwa2

1Department of Radiology, University of Florida, Jacksonville, FL, United States; 2Department of Medicine, University of Florida, Jacksonville, FL, United States

This study investigates the relationships between right-ventricle (RV)-related and pulmonary-artery (PA)-related parameters using MRI. A comprehensive MRI exam was developed for evaluating RV and PA, and tested on 25 PA hypertension(PAH) patients. Standard non-MRI measurements were collected. Comprehensive statistical analysis was conducted to study relationships between parameters, parameters significance, and data redundancy and reduction. The results showed strong correlations between most RV and PA parameters; and between most MRI parameters and PA pressure. There were redundancies between some within-group parameters. In conclusion, RV and PA are coupled and negatively affected in PAH. Both entities should be evaluated and interpreted together.

Keywords

acceleration accounted adjusted affected affecting agreement although analyses analyzed artery backward basic better brain characterized cine coded coefficient collinearity come comes component components comprehensive condition conducted confirmed consideration consisted correlated correlation correlations coupled coupling degrees deletion derived despite developed diagnosis diameter diastole diastolic divided dynamics dysfunction early ejection elevated eliminated encoding entities estimating evaluated evaluating evaluation exam example excluded fact finally flow fraction function functions furthermore goal gold grant heart hypertension identify included index insignificance insignificant insufficient interpretation interpreted introduced investigate lasted linear lunar measured mechanics minute minutes model modeling moderate much myocardial nature negatively newly occurred occurs others patient patients peak predicts pressure principal process processed pulmonary radiology reduced reduction redundancy reflected reflects regression related relationship restrictive roles scanned scanner significance slice specificity squared statistic statistical strain strong strongly survival systole together tolerance treatment types understand understanding variable variance variances vascular velocity ventricle ventricular vessel volume walk wave weak weakly