Meeting Banner
Abstract #3925

Pulmonary Artery 4D Flow MRI in Normal Volunteers and Pulmonary Hypertension

Pegah Entezari1, Susanne Schnell1, Octavia Biris1, Jeremy D. Collins1, Maria Carr1, Marie Wasielewski1, Jennifer McDonald1, Timothy J. Carroll1, 2, James Car

1Dept. of Radiology, Northwestern University, Chicago, IL, United States; 2Biomedical Engineering, Northwestern University, Evanston, IL, United States

This study evaluates the feasibility of 4D flow MRI for the assessment of 3D pulmonary flow characteristics in normal and hypertensive pulmonary arteries. The results of this pilot study demonstrate the feasibility of 4D flow MRI for the assessment of pulmonary flow characteristics and the ability to detect changes in PA flow compared to normal controls. Noticeably, patients with similar clinical presentation showed markedly different pulmonary 3D flow patterns indicating the potential of the methods to detect changes in pulmonary hemodynamics that may permit an improved characterization of the individual PAH severity.

Keywords

abnormal absence academic additional additionally administered agent aliasing alternative among approved arrow arrows arterial arteries artery assessment biomedical blood bock branches breathing characterization cine clinical cohort compliant comprehensive condition considering consists contrast control controls coronal coverage critical death dept detect diagnose diastole eddy emitted encoding engineering evaluation excellence except exemplary failure feasibility females find findings flow former foundation free full grading grant heart helical helix house hypertension importance improved indicating individual institute insufficiency invasiveness latter limes limitations located males maria marked markedly maxwell measured medicine mild monitor none northwestern noticeably open orientation path pathological patient patients patterns peak permit perpendicular pilot potential presence presentation progressive pronounced prospectively providing pulmonary radiology regularly representative resolution resolved retrograde scored severity since slice software solid spatial studies subjectivity subjects subsequent subsequently support swift synchronized system systole table temporal terms timothy tract trunk valve vascular velocities velocity ventricular vessel visualization visualized volunteer volunteers vortex wall white