Meeting Banner
Abstract #3886

Variable-Density Spiral Adenosine Stress Perfusion Imaging Detects Coronary Artery Disease with High Diagnostic Accuracy

Michael Salerno1, 2, Christopher T. Sica3, Craig H. Meyer4, Christopher M. Kramer5, 6

1Internal Medicine, Cardiology, University of Virginia, Charlottesville, Va, United States; 2Radiology, University of Virginia, Charlottesville, VA, United States; 3Center for NMR Research, Penn State Hershey Medical Center, Hershey, PA, United States; 4Biomedical Engineering, University of Virginia, Charlottesville, VA, United States; 5Radiology, University of Virginia, Charlottesville, Va, United States; 6Internal Medicine, Cardiology, University of Virginia, Charlottesville, VA, United States

We demonstrate that adenosine stress CMR using variable density spiral perfusion pulse sequences accurately detects obstructive coronary artery disease. These pulse sequences produce high quality perfusion images with minimal artifacts resulting in high diagnostic accuracy.

Keywords

abnormalities abnormality accuracy addition aimed amplitude anterior anticipate approved approximation artery artifacts aspect assessment automatic axis blinded blurring bypass cardiac cardiology chest chosen cine clearly clinically compensation conjugate consistent constant coronary correction corresponds coverage defect defects density described design detection detects diagnostic disease dropout duration enabling engineering enhanced enhancement evaluated evaluation excellent excluded fast field final five full function gadolinium good graded impede improve induced initial integrated interleaved internal late linear lobe maps medical medicine mild minimal moderate motion myocardial myocardium nearly nominal none novel obstructive optimized overall pain parallel pass patients performance perfusion peripheral pharmaceuticals poor presence preserving previously prior pulse quality radiology readers readout reconstructed reconstruction recovery reduced reduces reducing reduction relatively reliability resolution resolved rest reversible reviewers sampling saturation scale scanner scheduled score semi sensitivity severity short shot space spatial spiral statistic stress studies subject subjects support temporal trajectories trajectory true underwent utility utilization variable ventricle ventricular wall