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Abstract #3876

High Acceleration Quiescent-Interval Single Shot Magnetic Resonance Angiography at 1.5 and 3T

Christopher Glielmi1, Maria Carr2, Xiaoming Bi1, Peter Schmitt3, Mauricio Galizia2, 4, Judith Wood2, Robert R. Edelman4, Michael Markl2, James Carr2

1Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL, United States; 2Northwestern Memorial Hospital and Northwestern University Feinberg School of Medicine, Chicago, IL, United States; 3MR Application & Workflow Development, Siemens AG, Erlangen, Germany; 4NorthShore University HealthSystem, Evanston, IL, United States

Quiescent-Interval Single Shot (QISS) is a non-contrast MRA technique with proven clinical utility as an alternative to contrast-enhanced MRA (CE-MRA) at 1.5T. 3T QISS can potentially provide improved image quality and enable higher acceleration factors. This study compares QISS at 1.5 and 3T with high acceleration factors in healthy volunteers. In addition, the diagnostic quality of QISS at 3T in patients with peripheral artery disease (PAD) was evaluated. Results show improved image quality at 3T, maintained vessel conspicuity at high acceleration factors, and clinical utility of 3T QISS in patients with peripheral artery disease.

Keywords

accelerate acceleration acquisition addition adductor affected agreement alternative amplification angiography application arterial artery artifact artifacts assessed axial background bandwidth better blinded canal cardiovascular clinical cohort collateral comparable comparably complements confounded contamination contrast critical currently determine development diagnostic disease dividing enables enhanced evaluated even examples excellent extremity fair females femoral field foundation gated good grant healthy heart hospital improved inter interval kappa limb maintain males maria measured medical medicine memorial moderate muscle neither noise northwestern observer occlusion overall overlap parallel part partial patient patients pelvis performance peripheral peter pixel poor potential potentially press previous proven quality quiescent radiologists randomized receive reconstitution regardless reliability representative resolution scale scanned scanners school scored scores sector segmental sensitivity session shot significantly slices slightly spatially specificity statistic strength strengths studies subjects substantial subtracting suggest supported suppression thigh twelve unable utility varying venous vessel volunteer volunteers week wood