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Abstract #3866

Time-Resolved 3D Dynamic Contrast-Enhanced MR Angiography with Optimized Separate Auto Calibration Signal Lines

Yutaka Natsuaki1, Randall Kroeker2, Peter Schmitt3, J. Paul Finn4, Gerhard Laub5

1Siemens Healthcare, Los Angeles, CA, United States; 2Siemens Healthcare, Winnipeg, Canada; 3Siemens Healthcare, Erlangen, Germany; 4Radiology, UCLA, Los Angeles, CA, United States; 5Siemens Healthcare, San Francisco, CA, United States

Time-resolved 3D (4D) dynamic contrast-enhanced MR angiography (DCE-MRA) offers combined anatomic and hemodynamic information with fractional Gd contrast doses. Time-resolved imaging with stochastic trajectories (TWIST) is a view-sharing technique that acquires the peripheral k-space region with lower density while acquiring central data with full sampling. With a conventional TWIST, auto-calibration signal (ACS) lines for the parallel MRI are integrated in every central data acquisition. In the current work, we propose to modify the conventional TWIST by using an optimized separate ACS lines to improve the image quality of the peak carotid artery enhancements.

Keywords

accelerated acceleration acceptable according accumulated achieve acquiring acquisition acquisitions actual amounts anatomic angiography arrow arterial arteries artery artifacts basis beginning benefits calibration carotid cause central centric characterizing column combined complete consecutive contrast copied coverage crucial defined degrees density detected doses duration dynamic effective enhanced enhancement enhancements enough every example fidelity fink forward fractional full gradients grist hand help identical illustrated illustration improve improvements improves independent initial injection inner integrated invest lesions limitation longer maps match matrix meas minutes missing modify motion neighboring noise offers optimal optimized outer outside parallel partial pathologies patient patients peak percentage peripheral pixel portions potential prep profiles promising propose proposed qualitatively quality radiology reconstruct reconstructed reduced redundancy referred regulations resolution resolved retaining reveals sampled sampling scanned scanner scanning scheme sector separate separately separates series sharing significance significantly since source space spatial statistical stochastic subtracted superior temporal though trajectories trio twist typical utilized utilizes view visual volunteer yellow