Meeting Banner
Abstract #3842

3D Cine MRI of Mouse Heart with Concurrent Dephasing and Excitation

Naoharu Kobayashi1, Qiang Xiong2, Joseph Ippolito2, Jianyi Zhang2, Michael Garwood1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States; 2Cardiology, University of Minnesota Medical School, Minneapolis, MN, United States

3D magnetic resonance cine imaging of the mouse heart is highly challenging due to limited spatial and temporal resolution and cardiac and respiratory motion. We demonstrate CODE 3D cine MRI of mouse heart with prospective electrocardiogram gating, where the matrix size was cut down to reduce TR while keeping preferable spatial resolution by using a small surface coil and oversampled acquisition. And we applied sliding window reconstruction in order to increase the nominal temporal frame rate of the cine images. This method enabled high resolution 3D cine imaging with ~23 min at 9.4T.

Keywords

accelerated achieved acquisition administration advantage allow amount applied appropriate around artifacts assist asymmetric atrium attain axis bandwidth beginning blood briefly built cardiac cardiology challenging chest cine code coil complex compressed concurrent contrast correction cover coverage cycle decay decreased diameter diastolic difficulties easy electrocardiogram employed enables enhance excitation experience five folding frame frames free gated gating general glover gradients grant gridded heart heated highly holder homebuilt improvement inhaled interfered introduced limitation limited long loop magnet make manner many matrix medical mice motion mouse much muscles myocardium nominal outside oversampled oversampling peaks picked pipe placed poor position positioned posterior projection prospective pulsed radial ramp readout recently reconstructed reconstruction reduce relatively repeated repetition resolution respectively respiratory sampling saturated saturation school sensing septum sharing short since slab sliding space spatial spatially spiral studies suffers supplemented supported suppressing surface systolic temporal transform transit typically ultrashort undesirable undesired utilized variation ventricle view views wall whole width window