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Abstract #3839

Different Patterns of Myocardial Iron Overload by T2* Cardiovascular MR as Markers of Risk for Cardiac Complication in Thalassemia Major.

Antonella Meloni1, Vincenzo Positano1, Petra Keilberg1, Brunella Favilli1, Cristina Salvatori2, Letizia Gulino1, Gennaro Restaino3, Gianluca Valeri4, Massimo Midiri<su

1Cardiovascular MR Unit, Fondazione G. Monasterio CNR-Regione Toscana and Institute of Clinical Physiology, Pisa, Italy; 2Fondazione G. Monasterio CNR-Regione Toscana , Pisa, Italy; 3Centro di Ricerca e Formazione ad Alta Tecnologia nelle Scienze Biomediche "Giovanni Paolo II", Universit Cattolica del Sacro Cuore, Campobasso, Italy; 4Dipartimento di Radiologia, Azienda Ospedaliero-Universitaria Ospedali Riuniti "Umberto I-Lancisi-Salesi", Ancona, Italy; 5Istituto di Radiologia, Policlinico "Paolo Giaccone", Palermo, Italy; 6Centro trasfusionale e di microcitemia, Ospedale civile, Olbia, Italy

Homogeneous myocardial iron overload detected by multislice multiecho T2* MRI technique predicts a significantly higher risk to develop cardiac complications, especially heart failure, suggesting an intensive chelation therapy in this group of thalassemia major patients.

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Keywords

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