Meeting Banner
Abstract #3828

A New Approach for Noncontrast MR Imaging of Carotid Artery Disease

Na Zhang1, 2, Anqi Pei3, Lei Zhang1, 2, Xiaoxin Tong3, Xin Liu1, 2, Yiu-Cho Chung1, 2

1Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; 2Key Laboratory of Health Informatics, Chinese Academy of Sciences, Shenzhen, Guangdong, China; 3Department of Neurology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China

Carotid plaque imaging by MRI can characterize plaque components and allow assessment of plaque vulnerability. However, current technique requires Gd-based contrast and long examination time, making it inferior to color Doppler. We propose here a multi-contrast three dimensional (3D) carotid vessel wall imaging protocol without the use of Gd-based contrast. The protocol, consisting of T1w-SPACE, T2w-SPACE and MPRAGE, can be finished within 20 minutes including localization. Preliminary evaluation on volunteers and patients showed that total examination time was about 13 minutes excluding patient setup. The approach reduces operator dependency, provides more diagnostic information and better coverage compared to color Doppler.

Abstract PDF E-Poster Video

Keywords

academy agent allows approved arrows artery artifacts assessment attributed available better beyond bifurcation blood body carotid channels characterize china circulation clinically coil color commonly comparable components confirmed contrast contrasts density dependency described details development dimensional disease display efficiency examination except extend feasible flight flow form fusion gives good grant graphical health healthy heart help helps hemorrhage hence identified identify identifying inflammation informatics institutes insufficiency intensity laboratory latter light limitations localizing long longer lumen male match matched mechanism minutes moderate moody motion much needed operator participants patient patients people plaque poor preliminary prescribed propose proposed protocol protocols quality radiology reception recruited reduces registered relatively representative republic resolution reviewers risk saturation sciences score scores scout sets significantly simply slab sometimes space spatial specially statistically strong studies subject suggested system table takes thirdly tong tools trio typical unclear unfavorably useful variable various velocity vessel visualization visualized volunteer volunteers vulnerability wall whole width workstation yuan