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Abstract #3798

Quantitative Assessment of Highly Accelerated Real Time Cardiac Cine MRI Using Compressed Sensing and Parallel Imaging

Li Feng1, 2, Monvadi Barbara Srichai-Parsia1, Ruth P. Lim1, Alexis Harrison3, Wilson King4, Ganesh Adluru5, Edward Dibella5, Daniel Sodickson1, Ricardo Otazo

1Radiology, New York University School of Medicine, New York, United States; 2Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, United States; 3Internal Medicine, University of Utah, Salt Lake City, UT, United States; 4Division of Pediatric Cardiology, University of Utah, Salt Lake City, UT, United States; 5Radiology, University of Utah, Salt Lake City, UT, United States

Accurate assessment of cardiac size and function plays an important role in diagnosis and management of various heart diseases. For patients with impaired breath-hold capacity or arrhythmias, real time cine imaging may be more useful. Recently, highly accelerated real time cine imaging using a combination of compressed sensing and parallel imaging has been proposed with eight-fold acceleration. While this technique is promising for clinical applications, it has not been validated. The purpose of this study was to validate the relative accuracy of accelerated real time cine MRI for quantitative assessment of ventricular volumes and function in healthy human volunteers.

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Keywords

accelerated acceptable accurate achieve acquisition adaptive agreement analyses apical applications array arrhythmias assessment averaging axis basal beats best biomedical bland blinded body breath calculating capacity cardiac cardiologists cardiology cine city class clinical coefficient coil combination compressed computed conjugate correlation diagnosis diagnostic diastole diastolic difficult diseases division dummy electrocardiogram element equipped evaluation fold frames free function global good graduate healthy heart highly hold human identify impaired important includes independently institution inter invasive inverse iteratively king lake larger limit limitation linear magnetization males medicine observer parallel patients pediatric pixel plays pooled preliminary previously problem produced produces proposed prospective pulse quality quantification quantitative radiology randomized readers readout real reconstructed reconstruction relatively relevant reported representative resolution retrospectively role salt scanner school sciences sense sensing sensitivity sets short slice slices software space sparse spatial sponsor stacks steady stroke studies systole systolic table temporal transform triggered triggering type useful validated variability variation ventricular volume volunteers whole yield