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Abstract #3776

Feasibility of Dynamic 4D Whole Heart Viability Imaging Within a Single Breath-Hold Using Highly Accelerated Parallel Imaging and Compressed Sensing

Jian Xu1, 2, Li Feng1, Ricardo Otazo1, Barbara Srichai1, Ruth Lim1, Bhat Himanshu3, Kelly Anne Mcgorty1, Joseph Reaume1, Daniel Sodickson1

1Center for Biomedical Imaging, Radiology,New York University, New York, NY, United States; 2PolyTechnic Institute of New York University and Siemens Medical Solutions USA Inc., New York, NY, United States; 3Siemens Medical Solutions USA Inc., Charlestown, MA, United States

Myocardium viability imaging via late gadolinium hyper-enhancement (LGE) is usually imaged with an inversion recovery sequence. A multi-slice multi-planar 2D approach with an additional TI scout is commonly used in routine clinical practice. Highly accelerated whole volume LGE enables acquisition of all data at the same time point of contrast kinetics is desired. We evaluated the feasibility of whole heart dynamic 4D LGE imaging utilizing different TIs at different phases throughout the entire cardiac cycle within a single BH using 4D stack-of-star radial acquisition and k-t RASPS without the use of a precise TI scout.

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Keywords

accelerated achieved acquisition acquisitions additional adequately administrated apex apical applied approaches approval approximate array axis biomedical breath cardiac chosen cine clinical cohort coil combination commonly compressed conjugate consent contrast cycle delay dependence depicted determine developed diastole dynamic early efficacy employed enables encoding enhancement entire equipped ethics evaluation examined exhibits feasibility gadolinium gated good gradient healthy heart helps highly hold holds hyper illustrate improve individual informed institute institutional intensity inversion isotropic kinetics late male matrix maximize medical minimizes minutes motion myocardial myocardium need needed null nulling optimal overall parallel partial patients pixel planar position practice precise prepared proposed pulse quality radial radiology rasps readout recently reconstruction recovery reduced regard relatively requires resolution rotated sampling schematic schematically scout selected selective sensing several short slew slice slices software solutions space sparse spatial spokes stars still subject subjects subsequently suspected systole temporal trigger typically underway uniform usually utilized utilizing variation viability volume washout whole zero