Is Ribose and Creatine Supplementation Beneficial in Chronic Heart Failure? an in vivo 1H-MRS / 31P-MRS / Cine-MRI Study in Murine Hearts

Keywords

acquisition acquisitions acute adenine administration advanced aetiology agents allowed ameliorates applied approaches artery assess assessed available axis basic beneficial biochemical biochemistry black body cardiac cardiovascular characterization characterized chest chronic cine coil combination comprehensive console control controlled coronary corrected crucial cycles decrease depletion described despite diameter diastolic direct disease double drinking drop ejection elevated energetics evaluating expressed extreme fail failing failure faller feeding field finally fitted fold function gated harvested healthy heart hearts in vivo increasing infarct infarction initiated invasive kingdom lung magnet matching material metabolism mice model models morphology muscle myocardial nature needed nominal nucleotide nucleotides obvious oxford permanent phosphate pool potential preselected preserve pressure prevent previously protective protein protocol prove quantification rapid receiving remained representative resolution robust saturation secondary separated sets sham short since skeletal slice spectra statistical steps strategy studies subjected sufficient suggest suggested supplementation surface surgery systolic table therapeutic tune tuned underwent variable various ventricular view volume water weeks zero