Distinct Longitudinal Cortical Change in Frontotemporal Lobar Degeneration and Alzheimer's Disease

Keywords

accommodate accuracy advantages affect aging allows alternative amount analyses anatomically annualized anterior apply assess assesses atrophy automatic autopsy available benefit brain clinically cognitive cohort conclude conditions confirmed confounds contrast contrasts controls cook cortex cortical cost costs course currently decrease defined degeneration dementia depending designed designs diagnosed differ directly disease disorder disorders distinct duration education effective effectiveness effort emerging employ endpoint endpoints exhibit experimentally extract finally fluid focal focused framework frontal gender gives gray greater hypothesis ideal identify illustrate impact improve in vivo include inferior inhomogeneity jack known lancet leading learning likely lobar longitudinal machine manifestations matched measures modeling much needed neurology noise novel occipital occurs offset open optimal orbital parts pathology patients patterns poorly posterior potential power progress proven quantification quantifies quantitative radiology random reduction regionally regression relatedly relatively reserve reveals role scanning sessions significantly source specificity stages staging statistically studies subjects succeeded supports tracking treatment trials unbiased understood varied whole widely years