Meeting Banner
Abstract #3686

MR Elastography of Salivary Gland Masses: Preliminary Results

Kunwar Bhatia1, Philippe Garteiser2, Ralph Sinkus2, David Yeung3, Jing Yuan1, Yolanda Lee3, Ann King1, Anil Ahuja1

1Imaging and Interventional Radiology, Chinese University of Hong Kong, Shatin, N.T., Hong Kong; 2Department of Radiology and INSERM U773; 3Imaging and Interventional Radiology, Prince of Wales Hospital, Shatin, N.T., Hong Kong

Problem: Conventional imaging has suboptimal diagnostic accuracy for salivary masses. Methods: A study of MR elastography was conducted in nine patients with cytologically-confirmed salivary tumours using a customized mechanical driver and gradient echo MR sequences with fractional motion encoding. Recovered shear moduli (|G*| stiffness) for tumours and normal contralateral glands (controls) were compared using t-tests. Results: Pooled data of |G*| in tumours (0.830.47 kPa) overlapped with controls (0.590.32 kPa)(p=0.23). However, ratios of |G*|tumour:|G*|control for individual patients exceeded 1 in 8/9 cases (1.410.37, p=0.01). Conclusion: Preliminary results suggests that normalized shear moduli on MRE may differentiate salivary tumours from normal glands.

Abstract PDF E-Poster Video

Keywords

according acoustic analyses approval assessed assumed axial bipolar board body brain breast clustering comprised customized cytology density designed determine diagnosed diagnosis ding displacements driver effective eight elasticity elem encoding equating equation evaluate excitation feasible females fields flex flexible fractionally frequencies frequency gland glands gradient green hamburg healthy heart histology hong hospital identity indicate indicates indicating informed input inserted inversion isotropic king larger lesion lesions limited liver local lungs males manually maps masses mechanical mining modulus motion neck neoplasms novel ongoing oscillator patients pixel pooled preliminary presentation prince prostate protocol published pulse radiology recently reconstruction refocusing represents salivary sample sampled scanner sense several shear site sites sparse spatial spin statistical step stiffness strain subjects successful suggests theoretical thyroid tissue tissues tongue tonsils transferred utility valuating vary vector verse vibration viscoelasticity wales wave waves yuan