Investigating Tissue Microstructure Using Diffusion MRI: How Does the Resolution Limit of the Axon Diameter Relate to the Maximal Gradient Strength?

Keywords

according achievable active added allow apparent assumed assumes assuming assumptions attenuation away axon axons become blue brain cause close coefficient coil college components computing considered constrained constraining constructed contribute curves dashed decreased define defined described determined diameter diameters diffusion distinguished duration edges either encoding error even expect extending feature fits fitted fitting five fixed free frequency gives gradient gradients head helpful hence herein hindered human identical improving in vivo increasing independent inseparable insert intra intrinsic inverse laws leading limit limitation maximal medical microns minimal model moreover move noise optimal optimized perpendicular physics plotting potentially practically predicted predictions previously prior procedure proportional proposed prospects protocol protocols pulse pulsed quantification radiation reduce reduces reducing representing require resolution respectively restricted root scale scales scaling scanners selected series sets shell shorter significance simulations since square squared strategy strength strengths stronger structures studies suggests synthetic table theoretical theoretically theory threshold timing tissue units various varying versus water zero