Optimizing Diffusion Weighting Scheme by Cramer-Rao Lower Bound Analysis and Monte Carlo Simulation

Keywords

accuracy accurately achievable addition addressed affecting although analyses applied assessments autoimmune axial axon bars basis better bias blue bound brain built capability cell cells complex component composed conditions conducted consistent contaminations cord crossing crucial decreased dependent derived designed determine developed diffusion diffusivity displayed distributed distributing distribution edema effectively employed environment error examine examined experimental feasibility fiber fibers fixed fixing fold fraction frequently gradient gradients gray green grid improved improvement improves in vivo increasing indeed indicate infiltrating infiltration injury inner investigate isotropic linearly loss maximal minimizing model modeling mouse nervous noise novel optimization optimized optimizing partial pathological peak phantom plots positive potential precision preliminary previous properties prototype quality radial radiology reached recently restricted saint scheme schemes search selection shell shells significantly simulating simulation simulations since solution song spatial spectrum sphere spinal strength strongly studies subset successfully suggest suggested system tensor tessellated theoretical tissue tract typical uniformly variance variances vectors volume water whether white yielded