Accounting for Pre-Capillary Signal in Arterial Spin Labelling Perfusion Measurements

Keywords

account accounted accounting adding adopt approaches arbitrary arises arising arriving arterial arteries artery assumed biomedical blood bolus brain capillaries capillary central cerebral closely collected compartment component components computationally confirm confounding consider crushed crushing derived deviation diffusion efficient either empirical employed equilibrium estimation examine except exchange exhibiting existing experiment explained extend extra fail fitting flow generally give giving gradients healthy hypothesis identified impermeable implications important include included includes inclusion input inversion investigate kinetic kingdom label larger latter leading length macro magnetization manner masks matrix mixed model models overall oxford paired parameterized perfusion permeability peter potentially presence prior priors probabilistic pulsed quantification rapid reaches readout reducing reduction related reliably remained removed representative reside respectively resting saturation scaled shape share shrinkage significance simpler since slices sought source space spends spin stages still subject subjects substantial substantially support suppressed suppression taking theory tips tissue tool transit typical unlike varied vascular vessels volume water written zero