Meeting Banner
Abstract #3499

Revisiting the Determination of Myocardial Perfusion by T1 Based ASL Methods Applying Look-Locker Readout

Thomas Kampf1, Xavier Helluy2, Christian Herbert Ziener3, Peter Michael Jakob2, Wolfgang Rudolf Bauer4

1Experimental Physics 5, Universtity of Wuerzburg, Wuerzburg, Bavaria, Germany; 2Experimental Physics 5, University of Wuerzburg, Germany; 3Division of Radiology, German Cancer Research Center, Germany; 4Department of Internal Medicine I, Universitaetsklinikum Wuerzburg, Germany

The effect of the Look-Locker readout scheme on myocardial perfusion measurement applying ASL methods based on T1 mapping is investigated. Furthermore, the effect of partially inverting the left ventricular blood during the slice selective inversion is considered. Significant influence of each issue on the obtained perfusion is found.

Abstract PDF E-Poster Video

Keywords

absolute according accounts acts additionally apparent application applying arises arterial assessment assumed assumes belle blood calculating cancer capillary circulation coefficient coincide comparing compartment compartments completely conditions connected considered considering considers consists correct corrected correcting correction counterbalances cycle decreasing dependence describe described determination determined developed deviation diagnosis directly division drain ejection enter equation equations especially evaluates exchange existence experiment experimental exploits extra fast flow fraction fractions furthermore global grants great hampers heart ideal important incomplete increasing influence influencing inside internal inversion inverted inverts investigated issue issues labeling leads limit locker longitudinal look marks materials medical micro model monitoring mouse myocardial neglected neglecting normally noted overestimation partial partially partition perfusion peter physics properties pulses quantify radiology reach read readout recovery reduction regional repetition revisiting save scheme selective short significantly slice source special spin spins starting strong sufficient supported system theoretically theory tissue typical uncorrected underestimated underestimation vascular venous ventricle ventricular viewed volume water