Meeting Banner
Abstract #3483

Conductivity Imaging of an Ischemic Pig Heart Model Using Electric Properties Tomography

MAGNA25Tobias Voigt1, Andreas Schuster2, Masaki Ishida2, Christian Stehning3, Ulrich Katscher3, Amedeo Chiribiri2, Eike Nagel2, Tobias Schaeffter2

1Philips Research, London, United Kingdom; 2Kings College London, London, United Kingdom; 3Philips Research, Hamburg, Germany

In this work we present the application of EPT conductivity mapping in two isolated perfused pig hearts. Conductivity values of normally perfused heart tissue were compared to values in ischemic regions after a blockade of the left anterior descending artery (LAD). It could be shown that ischemic ventricular tissue is less conductive than healthy myocardium.

Keywords

according agreement anatomical animal anterior application artery axis balloon basis best black blast block blockade canine card cardiac catheter college compatible compute conductive conductivity continuous coronary cycle decrease descending described desired devices dielectric direct distinguish electric elsewhere employed extracellular feasible field fraction function gated gradient hamburg healthy heart hearts hole hours implanted important include independently induce infarction inflated injury interaction invasive irreversible isolated king kingdom leads likely literature loss mapping measured model myocardial myocardium normally occluded occlusion pass perfused perfusion phys place plays previously prior probes properties pulse quantitative reconstruction recovery reflects relation remote resolution resynchronization reversible role saturation scanner severe short slices space stabilize studies system table therapy tissue tomographic tomography trans transmit useful validated ventricle ventricular volume volumetric window