Meeting Banner
Abstract #3416

Synthetic T1rho Mapping with Multispectral Quantitative Magnetic Resonance Imaging: Initial Results with a Non Spin-Lock Technique

Hernan Jara1, Stephan William Anderson1, Osamu Sakai1

1Radiology, Boston University Medical Center, Boston, MA, United States

Purpose: To develop an algorithm for synthesizing T1rho maps using standard qMRI relaxometry instead of using direct spin-lock imaging acquisition techniques. Methods: A variant of the mixed turbo spin echo pulse sequence which is multispectral in PD, T1, and T2 was used at 3T. Images were processed with qMRI algorithms to generate T1 maps at varying spin-lock phase angles. Results: The resulting T1rho maps vary in appearance as a function of the spin-lock phase angle. Conclusion: A qMRI relaxometry-based technique for mapping the longitudinal relaxation time in the rotating frame T1rho has been developed and tested in the human head.

Abstract PDF E-Poster Video

Keywords

accepted acquisition acquisitions additional afford agreement allowing allows appearance applications availing avoids axial biologic brain breast cartilage caused clinical commonly conforming considerations contrast depicting develop developed differently dimension direct directly disease effective enabling equation excellent experimental field formula frame furthermore generates generation graham house imparting implemented in vivo increasing individual influence initial instead known larger limited liver lock longitudinal magnetization manipulations many mapping maps mathematical measuring medical mixed model muscle near noise parallel particular potential predicted processed programmed providing pulse quantification quantitative radiology relied resolution rotating scanner selected self sense simultaneous singularities slice slices specifically spin synthesizing synthetic systems theory tissue tissues transfer tumors turn upon useful variant varied weightings