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Abstract #3401

Tracking Muscle Tissue Displacement During Plantarflexion Excursion Using Non-Linear Deformation of Magnitude MR Images.

Usha Sinha1, Alec Biccum1, Shantanu Sinha2

1Physics, San Diego State University, San Diego, CA, United States; 2Radiology, University of California at San Diego, San Diego, CA, United States

The study focuses on the application of a non-linear warping algorithm based on optical flow to recover muscle tissue displacements from dynamic magnitude MR images. These were acquired on a 1.5-T GE scanner with a gated VE-PC imaging sequence while the subject exerted periodic ankle plantarflexion excursions. Tissue displacements were extracted from the magnitude images by warping the reference (first) image to images acquired at other phases. The deformation vectors recovered by the algorithm are visualized on a 2D grid; the grid deformation agreed with anticipated tissue displacements. The study shows the potential for deformations to be recovered directly from magnitude images.

Keywords

accommodate accuracy accurate acquiring acquisition actual aimed alone ankle anticipated application applied approaches array arrow artifacts bandwidth best board body bone calculation challenges channel cine clearly coil comparable conformance contours contrast convolution correction corrections correlating coverage currently decay deformation deformations denotes designed directly disappearance displacement displacements distorted drive dynamic eddy edges encoded encoding encumbered essentially excitations excursion excursions exists explored extract extracted feature field fields filter five flow gated gradients grid grids institutional intensities intensity internal iteration iteratively known landmarks latter lengths limited linear magnitude matrix model motion moving much muscle necessity need novel optical optimized orientation oriented overlaid overlay physics pixel pose potential preclude presumed propose quantitative radiology recover recovered recovering recovery recruited registering registration resolution resolutions segment segmented segmenting series several since slice spatial specially spin structures subjects subsequent successive sufficient tags temporal timescales tissue tracking transformation transformed typically variance vectors velocity views visualized warped warping water widths zero