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Abstract #3398

Automated Quantitation of CSF Volumes in Central Nervous System by MRI

Ahmet Murat Bagci1, Sudarshan Ranganathan1, Juan S. Gomez1, Byron Lam2, Noam Alperin1

1Radiology, University of Miami, Miami, FL, United States; 2Ophthalmology, University of Miami, Miami, FL, United States

The amount of cerebrospinal fluid (CSF) and its distribution with the central nervous system are central to our understanding of CSF related brain and spinal cord disorders. While reliable automated segmentation methods are available for brain, no such method is available for spinal CSF segmentation. Current segmentation of spinal CSF spaces relies on manual delineation which is time consuming and operator dependent. A methodology to delineate the volume of CSF within the whole central nervous system is presented and preliminary results were obtained from scans acquired before and after lumbar puncture.

Keywords

absorption accounting accuracy achieved acquisition agreement amount amounts anesthesia approximately assessed atlas automated automatically available background become believed best blue bone brain canal cause central cerebral cervical class classes classification clinically coefficient coefficients column compartments containing control cord covering cranial decrease defined degrees delineation demonstrating diagnosis dice disorders distribution documented epidural estimation every example excluding experienced extra fast fluid formation global good guided healthy hydrocephalus hypertension identify idiopathic immediately intensity intra isotropic know larger likely limited lumbar manual maps mask matrix measured measuring mixture nervous neuron occurred operator ophthalmology overall overlap partial patients portion post pressure previously prior projected protocol puncture quantification quantified quantify radiology reformatted regarding regional registered related reliable report reported resolution respectively rigid scanning segmentation segmented several soft software space spaces spinal spine steps subject summarized symphony system table template thoracic though tissue tool toolbox trans understanding uniformity uninterrupted upper useful ventricles ventricular volume volumes volumetric whole withdrawn