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Abstract #3299

Evaluation of Viscoelasticity in Early Degenerative Cartilage Using Apparent Diffusion Coefficient

Takako Aoki1, Atsuya Watanabe2, Naotaka Nitta3, Akira Furukawa1, Mamoru Niitsu4

1Radiological Science, Tokyo Metropolitan University, Arakawa-ku, Tokyo, Japan; 2Orthopedic Surgery, Teikyo University Chiba Medical Center, Anesaki, Chiba, Japan; 3Biomedical Sensing and Imaging, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan; 4Radiology, Saitama Medical University Hospital, Iruma-gun, Saitama, Japan

This is an interesting study on diffusion weighted MRI to assess articular cartilage in porcine knees by correlating ADC maps with viscosity coefficient and relaxation time measured by indentation testing.The strength of this article is the study design, performing diffusion weighted MRI on fresh porcine knees and using indentation testing as a measure of cartilage viscosity. Shortcomings are the inclusion of only normal knees. It would have been interesting to know the performance of diffusion weighted MRI to detect and quantify cartilage lesions.

Keywords

absorber acts apparent articular assessing biomedical cartilage coefficient confirm content correction correlate correlated correlation critical device diffusion distortion drawn early engineering evaluation femoral hosp indent indentation indicating industrial institute japan joint knee lateral lends mapping matrix measure measured medial medical months national needed notion objective physics planar porcine radiology role science shock shot slice specimen spin strength studies superficial support surgery table useful viscoelasticity viscosity water ween whole