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Abstract #3215

Microstructural Network Damage in Mesial Temporal Lobe Epilepsy

Michael Deppe1, Simon S. Keller1, Jan-Christoph Schne-Bake2, Siawoosh Mohammadi3, Bernd Weber2

1Neurology, University of Mnster, Mnster, Germany; 2Klinik und Poliklinik fuer Epileptologie und Life & Brain Center, Universitaetsklinikum Bonn, Bonn; 3Institute of Neurology, Wellcome Trust Centre for Neuroimaging, London, United Kingdom

 

Keywords

abnormalities alterations analyses anisotropy anterior atrophy axial bake bilateral brain clinical collaborative confined connectivity conservative considerable consistent context contrast controls corpus corrected correction cortical damage deterioration determine developed deviate diffusion distribution duration eddy encompassing epilepsy equal evaluation evidence exhibited fewer finally flair fractional frontal gradient healthy hemispheres human incorporating indicated indicates institute integrity intractable investigate investigation isotropic kernel kingdom life likely literature lobe long loss made mapping matrix medial medically monitoring network neurologically neurology normalization onset optimal orientation otherwise outside patients preferentially primarily processed project psychiatry radiological recently reduced reductions registration relaxed requires revealed review samples scanner sclerosis seizure side significantly slices smoothed spatial spatially statistical statistics still structural studied studies substantial substantially suggesting suggests supported surgical temporal tensor term thalamus threshold thresholded thresholds toolbox trio trust uncorrected unilateral unless video volume weber whether white widespread