Meeting Banner
Abstract #3095

Dynamic 3D Angiography with Pseudo Continuous Arterial Spin Labeling(PCASL) and Accelerated 3D Radial Acquisition

Huimin Wu1, Walter F. Block2, Patrick A. Turski3, Charles A. Mistretta1, Kevin M. Johnson1

1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Biomedical Engineering, University of Wisconsin-Madison; 3Radiology, University of Wisconsin-Madison

4D intracranial angiography with a pseudo continuous Arterial Spin Labeling (PCASL) tagging scheme and accelerated radial sampling pattern has been implemented. A feasibility study has been done on healthy volunteers and AVM patients and time-resolved images were acquired with temporal resolution of 200 msec. It has been demonstrated that the dynamic PCASL-VIPR technique can acquire a time series of dynamic inflow images with high 3D isotropic spatial resolution, and whole head coverage in a 7-minute scan. Quantitative analysis using time-of-arrival maps can also be performed on the time-resolved images.

Keywords

able accelerated acceleration acknowledge acquisition aneurysms angiography arrival arterial arteries artifacts assignment assistance attainable averaging background better blood bolus brain channel clearly clinical coil colorful completed composed consists continuous control course coverage create currently delineating design designed desired determined diagram diseases dispersion display distal done duration durations dynamic dynamics effective engineering entire every exam excellent expectation exploits extremely fair fashion feasibility feeding fitting frame generally generated global gradient grant gratefully head healthy hemisphere highly independently indications inferior inflow injection interleaved intravenous introduced investigate isotropic just labeling limited long loss maps matches medical minimize minutes modules motion nature occlusive optimized particularly pathological patient patients patterns physics potential preliminary previously projection projections pseudo pulse radial radiology randomly recently reconstruct resolution resolved sampling scanner segment segments series several simulations slab sparse spatial spin spoiled starting steno subjects suffers support suppression system tagging temporal took trajectories trajectory transparent useful vessel vessels visualization volunteer volunteers whole