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Abstract #3070

Long-Term Survival Study Showing Aging Effect on the Sensory Function of Peripheral Nervous System in Rats Using FMRI/fcMRI Under 9.4 Tesla

Rupeng Li1, Jack B. Stephenson IV2, Nicholas Flugstad2, Xiping Liu3, Christopher Pawela1, Ji-Geng Yan2, Hani S. Matloub2, James S. Hyde1

1Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI, United States; 3Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States

The influence of aging effect on peripheral sensory function was investigated using BOLD fMRI and fcMRI on rats. Results shows the sensory network in the cortex peaks at adult age. At the same time, sensory network at senile age shows strongest inter-voxel correlation, which indicates a more optimized structure at this period.

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Keywords

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