Meeting Banner
Abstract #2989

Quality Assurance of the Multi-Center Trial Prostate Cancer Localization with a Multiparametric MR Approach (PCaMAP): Initial Results

MAGNA25Marnix C. Maas1, Jurgen J. Ftterer2, Tom W.J. Scheenen2

1Radiology , Radboud University Nijmegen Medical Centre, Nijmegen, GLD, Netherlands; 2Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, GLD, Netherlands

Quality assurance measurements were performed for a prospective study involving 10 institutions, aimed at proving the diagnostic accuracy of 3T multi-modality MR imaging including high-resolution T2-weighted imaging, DWI, DCE and 3D MRSI in distinguishing carcinoma from other prostate tissue. ADCs, T1s and (Choline + Spermine + Creatine) / Citrate ratios were compared in 5 institutions in this preliminary study. Modest but statistically significant differences between institutions were found in all 3 categories. Whether this warrants corrections of the quantitative data for the prospective study will be subject to further investigation.

Keywords

according accounting accuracy acquisition anterior array assessment assurance axis body calibration calibrations cancer carcinoma caused central choline circular citrate clinical closer coils collected comparing concentrations conditions consisted consortium container containing contributions control correction created curves decay dedicated diagnostic differed diffusion distilled distinguishing doped edge enhanced examination experiment external fits fitted fitting fixed functional gels gold gradient grant green homogeneous horizontal identifier identify included indeed inhomogeneities inhomogeneity initial inner institutions linearized localization maps marginally measured measures medical metabolite metabolites next occur operator overall overlay parametric participating patient performance phantom phantoms placed positions posterior processed profiles progressive prospective prostate prostates protocol providing quality quantitative radiology receive related relatively remaining repeated report reported represent residuals resolution saturation scanner sealed section shim sites slice slices solution spectra spectral spectroscopic spectroscopy sphere spin spine spoiled squares standardized sucrose support system systems tended tissue transformed trial trio tube tubes variations various vendor warrant water whether white yielded