Meeting Banner
Abstract #2987

Improved Noncontact 3-Dimensional Breast MR Elastography

Jun Chen1, Roger Grimm1, Kevin Glaser1, Kugel Jennifer1, Kay Pelletier1, Richard Ehman1

1Radiology Department, Mayo Clinic, Rochester, MN, United States

Women in the US have a 1 in 8 chance of developing breast cancer. Contrast-enhanced MRI has a high sensitivity for breast cancer, but low specificity. Breast MRE is a promising tool for detecting malignancies, but the requirement for direct contact between the driver and the breast has several disadvantages. We have developed a noncontact driver design to avoid these problems and a 3D GRE MRE acquisition to image both breasts simultaneously. The results from 6 healthy female volunteers demonstrate the feasibility of these methods and motivate future studies of MRE for breast cancer diagnosis.

Abstract PDF E-Poster Video

Keywords

able accommodate acquisition adipose adjustable alone amplitude anal assessment aurora axes benign biopsy board born breast breasts cancer caused causing chance chemical clinic coil coils collect combined commercial compatible components consent contact continuous curl cycles deaths derivative described design designed detecting developed device differentiating dimensional direct directly driven driver drivers dummy earlier encoding exam feet female field fields filtered filtering free frequencies frequency generate generated generation glandular gradient greatly guided hypothesis improved improvements induced institutional invasive inversion kernels known liberty lifetime limiting local magnitude malignancies mammography materials matrix measuring mechanical million motion narrower newly novel offsets optimal optimized overestimation part penetration phys practice previous previously problems properties proposed quadrature radiation radiology recruited require respectively review risk roger sampling scanner screening shape shear simultaneously since soft sternum stiffness studies suitable tension tetrahedral tissue tissues today transmit twice typically unfortunately vector vibration volunteer volunteers warner water wave waves whole wider woman women written