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Abstract #2940

Intrapericardial Delivery of Imaging-Visible Microencapsulated Mesenchymal Stem Cells Using XFM Guidance

Yingli Fu1, Nicole Azene2, Tina Ehtiati3, Aaron Flammang3, Wesley Gilson3, Judy Cook4, Kathleen Gabrielson2, Clifford Weiss4, Jeff W. Bulte4, Peter V. Johns

1Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD, United States; 2Molecular & Comparative Pathobiology, Johns Hopkins University, Baltimore, MD, United States; 3Siemens Corporate Research, Baltimore, MD, United States; 4Radiology, Johns Hopkins University, Baltimore, MD, United States; 5Department of Medicine, Johns Hopkins University, Baltimore, MD, United States

X-ray fused with magnetic resonance imaging (XFM) takes advantage of both imaging modalities allowing cardiac function assessments and direct visualization of the vasculature. XFM guided microencapsulated stem cell delivery into the pericardium space was safe and would improve the retention of cellular therapeutics in the heart.

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Keywords

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