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Abstract #2923

MR-Guided Acoustic Shielding of the Ribs for Trans-Costal MRgHIFU Ablation in Liver

Magalie Viallon1, Lorena Petrusca2, Vincent Auboiroux2, Denis Morel3, Arnaud Mueller4, Maria I. Vargas1, Thomas Goget2, Sylvain Terraz1, Christoph D. Becker1

1Radiology Department, Geneva University Hospital, Geneva, Switzerland; 2Radiology Department, University of Geneva; 3Anesthesiology Department, University of Geneva; 4Radiology Department, HCL, CHU Lyon Sud, Lyon, France; 5Radiology Department, INSERM Rhone-Alpes, University of Geneva

One of the main challenge for the HIFU therapy in liver is to prevent the known high risk of collateral heating and thermal damage in the ribs and ribs-surrounding tissue. Ribs heating during liver MRgHIFU was a major obstacle for the translation of this technology into a clinical tool, whereas the size of the population potentially concerned by such a treatment is very large. This study investigates a new alternative to solve the problem of ribs heating, using dedicated MR-guided positioning of specific reflective strips for acoustic masking of the ribs.

Keywords

ablation able acoustic activation adaptive aligned alignment alone anesthesiology animal animals around array arrows available avoiding awakened beam body breath cage challenge coll collateral compatible comprised concerned contrast control coronal cost cross damage days decreases dedicated deposition diamonds digital directly easily effectiveness efficacy element elements elevation ending energy field finally focal focus free front general graphic green guided heating hepatic in vivo independent indicated inside inter interferometer late length liver made magnitude maps masking material measurable mechanical minute modes morel natural necropsy obstacles orange organs overlaid package parallelograms pathway patterns phantom phys pixel positioning post potentially prevent principle problem produced projection proof protection protectors radiology randomized rares reduction reflecting reflective reflectors resection respectively restricting ribs risk sacrificed scanner scattering selective shape sheep shielding slice software sparing spot stages steps strips studies surface surrounding synthesizing technology temperature therapy thermal thoracic tissue tool trans transducer translation treatment twice ultrasound upon uptake visible volumetric whole written