Hyperoxic Calibrated Quantitative FMRI for the Measurement of Regional Cerebral Metabolic Rate of Oxygen in a Hypermetabolic Swine Model

Keywords

acquisitions administered administering advantages although analyzed anesthetized animal animals approaches approved approximate approximately arterial assumed assuming baker biomedical blood body bold brain breathing built calibrated calibration calibrations carbon care cerebral challenge circuit clinical coefficient coil committee condition constant context cross custom delay dependent described determine determined developed dilution dioxide distinct done drawn duration errors estimation expense experiment experimental extraction fast faster feasibility feasible final flow fold funded gases goal heart humans inaccurate indicates induced infusion inhalation inhaled inspired institutional interleaved label labeling manually materials matrix measure measured measuring mechanically metabolic metabolism minute minutes model neurology normalized open optical oxygen paradigm percent pigs post preparation previously prior produced produces protocol proton quantitative radiology rapid readout receive recently reduction regional relationship representing respectively rest resting saturation scales scanner sensitivity several shot significantly simultaneous slice slight slightly sonata spin steady studies superior surface swine taken thirty tidal trend uncertainty validate validation wash whole yielded