Meeting Banner
Abstract #2856

Enhancement of Temporal Resolution and BOLD Sensitivity in Real-Time FMRI Using Multi-Slab Echo-Volumar Imaging

Stefan Posse1, 2, Elena Ackley1

1Neurology, University of New Mexico, Albuquerque, NM, United States; 2Electrical and Computer Engineering, Physics and Astronomy, University of New Mexico, Albuquerque, NM, United States

Real-time fMRI using multi-slab echo volumar imaging was performed with temporal resolution of 286 ms for whole brain acquisition and 136 ms for partial brain acquisition on a clinical 3 Tesla MRI scanner equipped with 12-channel head coil. Whole brain EVI with 286 ms temporal resolution of visual and motor tasks significantly increased average and maximum percent BOLD signal change, average and maximum t-score, and extent of activation compared with EPI. Partial brain EVI with 136 ms temporal resolution exhibited comparable percent signal change, enabled nonaliased detection of heartbeat correlated signal fluctuation and improved sampling of the hemodynamic response function.

Keywords

acceleration accounts acquisition acquisitions activated activation additionally almost analyzed array astronomy auditory autoregressive batch blocks bold brain channel close closed coil collected compartments computed computer considerable consisted consistently context contrast correlations cortex currently daemon deconvolution delays design determine dimension dimensions duration electrical employed engineering enhanced ensure equipped except excitation extended extent eyes fluctuation fold gated general geometrical greater head human identical improve improvement improves index integration inter introduced isotropic latencies linear long maps matrix measured measuring mechanisms methodology mode model modeling models moderate motion motor neurology noise onset open orientation overlaid paradigm parallel partial percent physics physiological posse previously quality quantification quantitative randomized readout real recent recently reconstructed reconstruction reduce reduction regional related reported required resolution resolve rest sampling scanner score scores selected selection sensitivity sequential serial several significantly simultaneous slab slabs software space spaces spatial spatially sqrt statistical studies subject subjects table tapping temporal tissue univariate versus viable visual whole