Meeting Banner
Abstract #2642

A Millimeter Scale Implanted Coil with an Integrated Wireless Amplifier for Imaging of the Rodent Kidney

Chunqi Qian1, Stephen Dodd1, Der-Yow Chen1, Joe Murphy-Boesch1, Alan Koretsky1

1LFMI/NINDS, National Institutes of Health, Bethesda, MD, United States

An implantable resonator with an integrated parametric amplifier has been constructed to provide enhanced localized sensitivity of internal organs in the rodent. The sample coil was one element of a non-linear double frequency resonator that mixed the MR signal with a pump frequency to produce an amplified output at the Larmor frequency. The resonator/wireless amplifier was 3mm x 3mm x 7mm in size, and it enabled high resolution images to be obtained to identify small vascular structures of a rat kidney in vivo.

Abstract PDF

Keywords

abdominal able amplification amplified amplifier anesthetized animal assuming bandwidth better blood bottom boundary carrier catheter cavity chosen chronically clearly close coil coils connected connection constructed construction coronal coupled coupling cross days detect detected detection determined development diameter dimension direct distance double effective effectively eliminate enable enabled enhanced enlarged external flash flow formed frequency gain gating glue glued hard heating homogeneity identification implantable implanted in vivo incision includes inductive inductively inside institutes integrated internal isolated kidney lateral leading localized locally located long loop loops made magnet medial meshes micro millimeter mixing motion motivation mutual national nuclear observing onset oriented orthogonal oscillation outputs outside overlap oxford parallel parametric penetration performance perpendicular pick placed portion potential power practice presence pulled pumping ready receive recently reception resolution resonated resonator resonators restricted retained retrospective returned rodent scale scheme sensitivity separation several slice solution sometimes spins still structures subsequently sufficient suitable surface threshold unfavorable utilized vascular view wired wireless