Meeting Banner
Abstract #2630

A 1H and 23Na Two Coil System Optimized for Imaging Mini-Pig Knee Cartilage at a Whole Body 7 Tesla MRI

Florian M. Meise1, Armin M. Nagel1, Tobias Gotterbarm2, Sebastian Hagmann2, Manuela Rsler1, Marc-Andre Weber3, Wolfhard Semmler1, Reiner Umathum1

1Dept. of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, BW, Germany; 2Dept. of Orthopaedic Surgery, University Hospital Heidelberg, Heidelberg, BW, Germany; 3Dept. of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, BW, Germany

Investigation of integration and vitality of cartilage transplants as well as the underlying cartilage matrix are important to optimize therapeutic approaches for cartilage damage. The aim of this study was to design an SNR optimized coil system for co-registered 1H and 23Na imaging of mini-pig knee cartilage at a whole body 7 Tesla MRI scanner, without the common loss of sensitivity due to a double resonant coil design.

Abstract PDF

Keywords

acknowledged acknowledgment allowed alternative analyze anatomically approaches appropriate arrow arrows available avoid biomedical birdcage body cable cancer capacitors cartilage caused channels circuits circumscribed coil coils college combination common complementary compromised concept conditions conductor corp coupling covering damage datasets decreased dept design designed designs detail developed diagnostic double especially exchangeable features feed field filter final fitting fixed geometry gratefully help highlights homogeneous hospital imperial important improvements in vivo injured injury insert integration investigation isotropic keeping knee knees known least length loss losses macroscopic mark matching matrix medical mini network optimize optimized overall parallel patient performance physics placed plate port positioning post press provoked radiology rapid realized reasonable reduce regeneration registered registration removable reproducible resolution resolved resonant respectively sample samples scanner schematic sensitivity setup setups short sodium solenoid spin split stable structure studies surgery symmetric system systems table therapeutic thin transplants trap tuned tuning turns ultra underlying usually view vitality weber whole wolf wound