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Abstract #2525

MR Elastography of the Prostate Using an Endorectal Coil for Actuation: Feasibility in a Phantom and Porcine Prostate

Gregor Thrmer1, Martin Reiss-Zimmermann1, Josephin Otto1, Nikita Garnov1, Michael Moche1, Thomas Kahn1, Harald Busse1

1Dept. of Diagnostic and Interventional Radiology, Leipzig University Hospital, Leipzig, Saxony, Germany

MRE is an emerging technique that measures the propagation of mechanical waves to noninvasively determine the viscoelastic tissue properties. As such, it provides complimentary information to common morphological and functional MRI data, has already been evaluated in the breast and liver, and holds promise to improve prostate diagnostics as well. Previous prostate MRE work was partially limited by a suboptimal coupling of the mechanical waves into the prostate gland. This work describes a new concept for endorectal MRE at 3T and presents preliminary results in a phantom and a porcine prostate.

Keywords

achieve acknowledged acquisition actual actuation actuator adapted advantage application arrow assisting background balloon basic blocked blue body breast cadaver cancer carbon channel circles clearly clinical close coded coil components computed concept connected cord coronal coupled dept describes design details device devoted diagnostics diameter diffusion displacements distal drawing ellipses embedded emerging examination excitation expansion experiment feasibility fixed frequencies frequency generate generated generates gland housing identification identified implementation improve inclusions inner inset isotropic like local located martin measured measures mechanical mechanism model modified moduli modulus motion mounted muscle object onto orthogonal oscillations overlaid overlay patterns perfusion permits perpendicular phantom placed plastic porcine position potential preliminary previous promise propagate propagation properties prostate providing proximity radiology reflections reported requires resolution respectively reversing sack scanner schematic section sensitive setup shear slice spatial spherical stiffening stress structures substantially supine surface surrounding table telescopic thank tissue tissues tract transformed triggered trio validation vendor vibration vibrations viscoelastic wave waves